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Chemical structure of SP 600125

GC15344

SP 600125

Also known as 14,15-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-1(15),2,4,6,9(16),10,12-heptaen-8-one

SP 600125 is an orally active, reversible, selective, ATP-competitive JNK inhibitor with IC50 of 40, 40, and 90 nM for JNK1, JNK2, and JNK3, respectively· SP 600125 is commonly used in the research of ovarian cancer, tumors, Parkinson's disease (PD), breast cancer, and asthma

ChemicalCAS129-56-6MW220.23FormulaC14H8N2O
CAS number
129-56-6
Molecular weight
220.23
Formula
C14H8N2O
Solubility
≥ 11mg/mL in DMSO, ≥ 2·56 mg/mL in EtOH with gentle warming
InChIKey
ACPOUJIDANTYHO-UHFFFAOYSA-N
Catalogue number
GC15344
Brand
GLPBIO
Computed properties PubChem CID 8515 · XLogP 2.7 · TPSA 45.8 Ų · H-bond donors 1
XLogP
2.7
TPSA
45.8 Ų
H-bond donors
1
H-bond acceptors
2
Rotatable bonds
0
Heavy atoms
17

SMILES C1=CC=C2C(=C1)C3=NNC4=CC=CC(=C43)C2=O

Computed descriptors from PubChem (CID 8515), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.