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Chemical structure of Vandetanib

GC15022

Vandetanib

Also listed as Vandetanib (ZD6474)

Vandetanib (ZD6474) (D6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM)· Vandetanib (ZD6474) also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM)

ChemicalCAS443913-73-3MW475.35FormulaC22H24BrFN4O2
CAS number
443913-73-3
Molecular weight
475.35
Formula
C22H24BrFN4O2
Solubility
≥ 11·9mg/mL in DMSO with gentle warming
InChIKey
UHTHHESEBZOYNR-UHFFFAOYSA-N
Catalogue number
GC15022
Brand
GLPBIO
Computed properties PubChem CID 3081361 · XLogP 4.9 · TPSA 59.5 Ų · H-bond donors 1
XLogP
4.9
TPSA
59.5 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
30

SMILES CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC

Computed descriptors from PubChem (CID 3081361), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.