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Chemical structure of Crenolanib

GC14906

Crenolanib

Also listed as Crenolanib (CP-868596)

Crenolanib (CP-868596) is a potent and selective inhibitor of wild-type and mutant isoforms of the class III receptor tyrosine kinases FLT3 and PDGFRα/β with Kds of 0·74 nM and 2·1 nM/3·2 nM, respectively

ChemicalCAS670220-88-9MW443.54FormulaC26H29N5O2
CAS number
670220-88-9
Molecular weight
443.54
Formula
C26H29N5O2
Solubility
≥ 22·2mg/mL in DMSO, ≥ 2·5 mg/mL in EtOH with ultrasonic
InChIKey
DYNHJHQFHQTFTP-UHFFFAOYSA-N
Catalogue number
GC14906
Brand
GLPBIO
Computed properties PubChem CID 10366136 · XLogP 3.7 · TPSA 78.4 Ų · H-bond donors 1
XLogP
3.7
TPSA
78.4 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
33

SMILES CC1(COC1)COC2=CC3=C(C=C2)N(C=N3)C4=NC5=C(C=CC=C5N6CCC(CC6)N)C=C4

Computed descriptors from PubChem (CID 10366136), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.