GC14815
GMX1778 (CHS828)
Also known as 2-[6-(4-chlorophenoxy)hexyl]-1-cyano-3-pyridin-4-ylguanidine
GMX1778 (CHS828) (GMX1778) is a competitive inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), with an IC50 less than 25 nM· GMX1778 (CHS828) (GMX1778) exerts a cytotoxic effect by decreasing the cellular level of NAD+ and exhibits a potent anticancer activity
ChemicalCAS200484-11-3MW371.86FormulaC19H22ClN5O
- CAS number
- 200484-11-3
- Molecular weight
- 371.86
- Formula
- C19H22ClN5O
- Solubility
- ≥ 18·3mg/mL in DMSO
- InChIKey
- BOIPLTNGIAPDBY-UHFFFAOYSA-N
- Catalogue number
- GC14815
- Brand
- GLPBIO
Computed properties PubChem CID 148198 · XLogP 4.3 · TPSA 82.3 Ų · H-bond donors 2
- XLogP
- 4.3
- TPSA
- 82.3 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Rotatable bonds
- 11
- Heavy atoms
- 26
SMILES C1=CC(=CC=C1OCCCCCCN=C(NC#N)NC2=CC=NC=C2)Cl
Computed descriptors from PubChem (CID 148198), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il