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Chemical structure of Rociletinib

GC14695

Rociletinib

Also listed as CO-1686 (AVL-301)

A selective inhibitor of mutant EGFR

ChemicalCAS1374640-70-6MW555.55FormulaC27H28F3N7O3
CAS number
1374640-70-6
Molecular weight
555.55
Formula
C27H28F3N7O3
Solubility
≥ 27·8 mg/mL in DMSO, ≥ 4·68 mg/mL in EtOH with ultrasonic and warming
InChIKey
HUFOZJXAKZVRNJ-UHFFFAOYSA-N
Catalogue number
GC14695
Brand
GLPBIO
Computed properties PubChem CID 57335384 · XLogP 4 · TPSA 112 Ų · H-bond donors 3
XLogP
4
TPSA
112 Ų
H-bond donors
3
H-bond acceptors
11
Rotatable bonds
8
Heavy atoms
40

SMILES CC(=O)N1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=C(C(=N3)NC4=CC(=CC=C4)NC(=O)C=C)C(F)(F)F)OC

Computed descriptors from PubChem (CID 57335384), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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