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Chemical structure of CBL0137

GC14634

CBL0137

Also known as 1-[6-acetyl-9-[2-(propan-2-ylamino)ethyl]carbazol-3-yl]ethanone

CBL0137 is a first-in-class small molecule compound that targets the FACT complex to modulate chromatin structure and gene expression· It can inhibit the activity of the NF-κB signaling pathway and has anti-cancer and anti-inflammatory properties

ChemicalCAS1197996-80-7MW336.4FormulaC21H24N2O2
CAS number
1197996-80-7
Molecular weight
336.4
Formula
C21H24N2O2
Solubility
≤2mg/ml in ethanol;5mg/ml in DMSO;5mg/ml in dimethyl formamide
InChIKey
JKCSODVERGVDLT-UHFFFAOYSA-N
Catalogue number
GC14634
Brand
GLPBIO
Computed properties PubChem CID 44519124 · XLogP 3 · TPSA 51.1 Ų · H-bond donors 1
XLogP
3
TPSA
51.1 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
6
Heavy atoms
25

SMILES CC(C)NCCN1C2=C(C=C(C=C2)C(=O)C)C3=C1C=CC(=C3)C(=O)C

Computed descriptors from PubChem (CID 44519124), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.