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Chemical structure of AP20187

GC14498

AP20187

Also known as [(1R)-3-(3,4-dimethoxyphenyl)-1-[3-[2-[[2-[[[2-[3-[(1R)-3-(3,4-dimethoxyphenyl)-1-[(2S)-1-[(2S)-2-(3,4,5-trimethoxyphenyl)butanoyl]piperidine-2-carbonyl]oxypropyl]phenoxy]acetyl]amino]methyl]-3-(dimethylamino)propyl]amino]-2-oxoethoxy]phenyl]propyl] (2S)-1-[(2S)-2-(3,4,5-trimethoxyphenyl)butanoyl]piperidine-2-carboxylate

AP20187 is a synthetic dimerizer compound that can induce the dimerization of proteins engineered to contain FKBP (FK506-binding protein) domains· AP20187 has been widely used in various biological research and therapeutic applications to control protein-protein interactions and regulate cellular processes

ChemicalCAS195514-80-8MW1482.75FormulaC82H107N5O20
CAS number
195514-80-8
Molecular weight
1482.75
Formula
C82H107N5O20
Solubility
≥ 74·1375mg/mL in DMSO, ≥ 50mg/ml in 75% ethanol aqueous solution
InChIKey
NSBGUMKAXUXKGI-BPNHAYRBSA-N
Catalogue number
GC14498
Brand
GLPBIO
Computed properties PubChem CID 78357784 · XLogP 12.2 · TPSA 265 Ų · H-bond donors 2
XLogP
12.2
TPSA
265 Ų
H-bond donors
2
H-bond acceptors
21
Rotatable bonds
42
Heavy atoms
107

SMILES CC[C@@H](C1=CC(=C(C(=C1)OC)OC)OC)C(=O)N2CCCC[C@H]2C(=O)O[C@H](CCC3=CC(=C(C=C3)OC)OC)C4=CC(=CC=C4)OCC(=O)NCC(CNC(=O)COC5=CC=CC(=C5)[C@@H](CCC6=CC(=C(C=C6)OC)OC)OC(=O)[C@@H]7CCCCN7C(=O)[C@@H](CC)C8=CC(=C(C(=C8)OC)OC)OC)CN(C)C

Computed descriptors from PubChem (CID 78357784), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.