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Chemical structure of Ponatinib

GC14396

Ponatinib

Also listed as Ponatinib (AP24534)

Ponatinib (AP24534) (AP24534) is an orally active multi-targeted kinase inhibitor with IC50s of 0·37 nM, 1·1 nM, 1·5 nM, 2·2 nM, and 5·4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively

ChemicalCAS943319-70-8MW532.56FormulaC29H27F3N6O
CAS number
943319-70-8
Molecular weight
532.56
Formula
C29H27F3N6O
Solubility
≥ 53·3mg/mL in DMSO
InChIKey
PHXJVRSECIGDHY-UHFFFAOYSA-N
Catalogue number
GC14396
Brand
GLPBIO
Computed properties PubChem CID 24826799 · XLogP 4.1 · TPSA 65.8 Ų · H-bond donors 1
XLogP
4.1
TPSA
65.8 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
6
Heavy atoms
39

SMILES CC1=C(C=C(C=C1)C(=O)NC2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)C#CC4=CN=C5N4N=CC=C5

Computed descriptors from PubChem (CID 24826799), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.