GC14371
LY3023414
Also known as 8-[5-(2-hydroxypropan-2-yl)-3-pyridinyl]-1-[(2S)-2-methoxypropyl]-3-methylimidazo[4,5-c]quinolin-2-one
LY3023414 (LY3023414) potently and selectively inhibits class I PI3K isoforms, DNA-PK, and mTORC1/2 with IC50s of 6·07 nM, 77·6 nM, 38 nM, 23·8 nM, 4·24 nM and 165 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ, DNA-PK and mTOR, respectively· LY3023414 potently inhibits mTORC1/2 at low nanomolar concentrations
ChemicalCAS1386874-06-1MW406.48FormulaC23H26N4O3
- CAS number
- 1386874-06-1
- Molecular weight
- 406.48
- Formula
- C23H26N4O3
- Solubility
- ≥ 40·6mg/mL in DMSO
- InChIKey
- ACCFLVVUVBJNGT-AWEZNQCLSA-N
- Catalogue number
- GC14371
- Brand
- GLPBIO
Computed properties PubChem CID 57519748 · XLogP 1.7 · TPSA 78.8 Ų · H-bond donors 1
- XLogP
- 1.7
- TPSA
- 78.8 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Rotatable bonds
- 5
- Heavy atoms
- 30
SMILES C[C@@H](CN1C2=C3C=C(C=CC3=NC=C2N(C1=O)C)C4=CC(=CN=C4)C(C)(C)O)OC
Computed descriptors from PubChem (CID 57519748), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il