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Chemical structure of GW 6471

GC14187

GW 6471

Also known as N-[(2S)-3-[4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]-2-[[(Z)-4-oxo-4-[4-(trifluoromethyl)phenyl]but-2-en-2-yl]amino]propyl]propanamide

GW 6471 is a potent dual PARα/γ antagonist with anti-proliferative activity in vivo and in vitro· The IC50 values of GW 6471 binding affinity to PPARα and PPARγ are 95·3 ± 42·0 nM and 39·4 ± 18·2 nM, respectively· GW 6471 can be used in cancer research

ChemicalCAS880635-03-0MW619.67FormulaC35H36F3N3O4
CAS number
880635-03-0
Molecular weight
619.67
Formula
C35H36F3N3O4
Solubility
DMF: 20 mg/ml,DMF:PBS(pH7·2) (1:2): 0·33 mg/ml,DMSO: 11 mg/ml,Ethanol: 10 mg/ml
InChIKey
TYEFSRMOUXWTDN-DYQICHDWSA-N
Catalogue number
GC14187
Brand
GLPBIO
Computed properties PubChem CID 446738 · XLogP 7.9 · TPSA 93.5 Ų · H-bond donors 2
XLogP
7.9
TPSA
93.5 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
14
Heavy atoms
45

SMILES CCC(=O)NC[C@H](CC1=CC=C(C=C1)OCCC2=C(OC(=N2)C3=CC=CC=C3)C)N/C(=C\C(=O)C4=CC=C(C=C4)C(F)(F)F)/C

Computed descriptors from PubChem (CID 446738), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.