GC13841
JNK-IN-8
Also known as 3-[[(E)-4-(dimethylamino)but-2-enoyl]amino]-N-[3-methyl-4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
JNK-IN-8 is the first irreversible JNK inhibitor that acts on JNK1, JNK2, and JNK3 with high specificity, with IC50 values of 4·7 nM, 18·7 nM, and 1 nM in the A375 cell line, respectively
ChemicalCAS1410880-22-6MW507.59FormulaC29H29N7O2
- CAS number
- 1410880-22-6
- Molecular weight
- 507.59
- Formula
- C29H29N7O2
- Solubility
- ≥ 25·4 mg/mL in DMSO, ≥ 9·24 mg/mL in EtOH with ultrasonic and warming
- InChIKey
- GJFCSAPFHAXMSF-UXBLZVDNSA-N
- Catalogue number
- GC13841
- Brand
- GLPBIO
Computed properties PubChem CID 57340686 · XLogP 3.3 · TPSA 112 Ų · H-bond donors 3
- XLogP
- 3.3
- TPSA
- 112 Ų
- H-bond donors
- 3
- H-bond acceptors
- 7
- Rotatable bonds
- 9
- Heavy atoms
- 38
SMILES CC1=C(C=CC(=C1)NC(=O)C2=CC(=CC=C2)NC(=O)/C=C/CN(C)C)NC3=NC=CC(=N3)C4=CN=CC=C4
Computed descriptors from PubChem (CID 57340686), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il