GC13761
Sapitinib
Also listed as AZD8931 (Sapitinib)
AZD8931 (Sapitinib) (AZD-8931) is a reversible, ATP competitive EGFR inhibitor of with IC50s of 4, 3 and 4 nM for EGFR, ErbB2 and ErbB3 in cells, respectively
ChemicalCAS848942-61-0MW473.93FormulaC23H25ClFN5O3
- CAS number
- 848942-61-0
- Molecular weight
- 473.93
- Formula
- C23H25ClFN5O3
- Solubility
- ≥ 23·7 mg/mL in DMSO, ≥ 57·8 mg/mL in EtOH with gentle warming
- InChIKey
- DFJSJLGUIXFDJP-UHFFFAOYSA-N
- Catalogue number
- GC13761
- Brand
- GLPBIO
Computed properties PubChem CID 11488320 · XLogP 4 · TPSA 88.6 Ų · H-bond donors 2
- XLogP
- 4
- TPSA
- 88.6 Ų
- H-bond donors
- 2
- H-bond acceptors
- 8
- Rotatable bonds
- 7
- Heavy atoms
- 33
SMILES CNC(=O)CN1CCC(CC1)OC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C(=CC=C4)Cl)F)OC
Computed descriptors from PubChem (CID 11488320), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il