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Chemical structure of GSK690693

GC13696

GSK690693

Also known as 4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[[(3S)-piperidin-3-yl]methoxy]imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol

GSK690693 is an ATP-competitive, low nanomolar inhibitor of Akt kinases with IC50 values of 2, 13, and 9 nM for Akt1, 2, and 3, respectively

ChemicalCAS937174-76-0MW425.48FormulaC21H27N7O3
CAS number
937174-76-0
Molecular weight
425.48
Formula
C21H27N7O3
Solubility
≥ 21·25mg/mL in DMSO
InChIKey
KGPGFQWBCSZGEL-ZDUSSCGKSA-N
Catalogue number
GC13696
Brand
GLPBIO
Computed properties PubChem CID 16725726 · XLogP 0.3 · TPSA 137 Ų · H-bond donors 3
XLogP
0.3
TPSA
137 Ų
H-bond donors
3
H-bond acceptors
9
Rotatable bonds
7
Heavy atoms
31

SMILES CCN1C2=C(C(=NC=C2OC[C@H]3CCCNC3)C#CC(C)(C)O)N=C1C4=NON=C4N

Computed descriptors from PubChem (CID 16725726), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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