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Chemical structure of CC-223

GC13648

CC-223

Also known as 3-[6-(2-hydroxypropan-2-yl)-3-pyridinyl]-5-(4-methoxycyclohexyl)-7,8-dihydropyrazino[2,3-b]pyrazin-6-one

CC-223 (CC-223) is a potent, selective, and orally bioavailable inhibitor of mTOR kinase, with an IC50 value for mTOR kinase of 16 nM· CC-223 inhibits both mTORC1 and mTORC2

ChemicalCAS1228013-30-6MW397.47FormulaC21H27N5O3
CAS number
1228013-30-6
Molecular weight
397.47
Formula
C21H27N5O3
Solubility
DMF： 30 mg/mL,DMF：PBS(pH 7·2)(1：1)： 0·5 mg/mL,DMSO： 25 mg/mL,Ethanol： 20 mg/mL
InChIKey
UFKLYTOEMRFKAD-UHFFFAOYSA-N
Catalogue number
GC13648
Brand
GLPBIO
Computed properties PubChem CID 58298316 · XLogP 1.1 · TPSA 100 Ų · H-bond donors 2
XLogP
1.1
TPSA
100 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
4
Heavy atoms
29

SMILES CC(C)(C1=NC=C(C=C1)C2=CN=C3C(=N2)N(C(=O)CN3)C4CCC(CC4)OC)O

Computed descriptors from PubChem (CID 58298316), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.