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Chemical structure of MGCD-265

GC13598

MGCD-265

Also known as N-[[3-fluoro-4-[2-(1-methylimidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxyphenyl]carbamothioyl]-2-phenylacetamide

MGCD-265 is a potent and oral active inhibitor of c-Met and VEGFR2 tyrosine kinases, with IC50s of 29 nM and 10 nM, respectively· MGCD-265 has significant antitumor activity

ChemicalCAS875337-44-3MW517.6FormulaC26H20FN5O2S2
CAS number
875337-44-3
Molecular weight
517.6
Formula
C26H20FN5O2S2
Solubility
≥ 25·9mg/mL in DMSO
InChIKey
UFICVEHDQUKCEA-UHFFFAOYSA-N
Catalogue number
GC13598
Brand
GLPBIO
Computed properties PubChem CID 24901704 · XLogP 4.9 · TPSA 141 Ų · H-bond donors 2
XLogP
4.9
TPSA
141 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
36

SMILES CN1C=C(N=C1)C2=CC3=NC=CC(=C3S2)OC4=C(C=C(C=C4)NC(=S)NC(=O)CC5=CC=CC=C5)F

Computed descriptors from PubChem (CID 24901704), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.