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Chemical structure of ML351

GC13386

ML351

Also known as 5-(methylamino)-2-naphthalen-1-yl-1,3-oxazole-4-carbonitrile

ML351 is a selective 15-lipoxygenase-1 (15-LOX-1; 12/15-LOX) inhibitor with an IC50 of 200nM

ChemicalCAS847163-28-4MW249.3FormulaC15H11N3O
CAS number
847163-28-4
Molecular weight
249.3
Formula
C15H11N3O
Solubility
≤25mg/ml in DMSO; 25mg/ml in dimethyl formamide
InChIKey
DYXYXTDIFMDJIR-UHFFFAOYSA-N
Catalogue number
GC13386
Brand
GLPBIO
Computed properties PubChem CID 664510 · XLogP 4.2 · TPSA 61.9 Ų · H-bond donors 1
XLogP
4.2
TPSA
61.9 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
2
Heavy atoms
19

SMILES CNC1=C(N=C(O1)C2=CC=CC3=CC=CC=C32)C#N

Computed descriptors from PubChem (CID 664510), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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