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Chemical structure of TOK-001

GC13362

TOK-001

Also known as (3S,8R,9S,10R,13S,14S)-17-(benzimidazol-1-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-ol

TOK-001 (TOK-001) is a multifunctional antiandrogen and CYP17 inhibitor (IC50=47 nM) in castration resistant prostate cancer (CRPC)

ChemicalCAS851983-85-2MW388.56FormulaC26H32N2O
CAS number
851983-85-2
Molecular weight
388.56
Formula
C26H32N2O
Solubility
≥ 12·4mg/mL in DMSO
InChIKey
PAFKTGFSEFKSQG-PAASFTFBSA-N
Catalogue number
GC13362
Brand
GLPBIO
Computed properties PubChem CID 11188409 · XLogP 5.2 · TPSA 38.1 Ų · H-bond donors 1
XLogP
5.2
TPSA
38.1 Ų
H-bond donors
1
H-bond acceptors
2
Rotatable bonds
1
Heavy atoms
29

SMILES C[C@]12CC[C@@H](CC1=CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC=C4N5C=NC6=CC=CC=C65)C)O

Computed descriptors from PubChem (CID 11188409), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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