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Chemical structure of NAS-181

GC13298

NAS-181

Also known as methanesulfonic acid;(2R)-2-[[3-(morpholin-4-ylmethyl)-2H-chromen-8-yl]oxymethyl]morpholine

NAS181 is a potent and selective antagonist of rat 5-HT1B receptor, with a Ki of 47 nM

ChemicalCAS1217474-40-2MW538.63FormulaC19H26N2O4·2CH3SO3H
CAS number
1217474-40-2
Molecular weight
538.63
Formula
C19H26N2O4·2CH3SO3H
Solubility
<53·86mg/ml in Water; <53·86mg/ml in DMSO
InChIKey
WMRMIRRDPBKNMY-ZEECNFPPSA-N
Catalogue number
GC13298
Brand
GLPBIO
Computed properties PubChem CID 45073445 · TPSA 178 Ų · H-bond donors 3 · H-bond acceptors 12
TPSA
178 Ų
H-bond donors
3
H-bond acceptors
12
Rotatable bonds
5
Heavy atoms
35

SMILES CS(=O)(=O)O.CS(=O)(=O)O.C1CO[C@H](CN1)COC2=CC=CC3=C2OCC(=C3)CN4CCOCC4

Computed descriptors from PubChem (CID 45073445), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.