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Chemical structure of WZ3146

GC13213

WZ3146

Also known as N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Mutant EGFR inhibitor, potent and irreversible

ChemicalCAS1214265-56-1MW464.95FormulaC24H25ClN6O2
CAS number
1214265-56-1
Molecular weight
464.95
Formula
C24H25ClN6O2
Solubility
≥ 23·25mg/mL in DMSO with gentle warming
InChIKey
APHGZZPEOCCYNO-UHFFFAOYSA-N
Catalogue number
GC13213
Brand
GLPBIO
Computed properties PubChem CID 44607360 · XLogP 4.3 · TPSA 82.6 Ų · H-bond donors 2
XLogP
4.3
TPSA
82.6 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
7
Heavy atoms
33

SMILES CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)OC4=CC=CC(=C4)NC(=O)C=C)Cl

Computed descriptors from PubChem (CID 44607360), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.