GC13044
17-DMAG (Alvespimycin) HCl
Also known as [(4E,6Z,8R,9R,10E,12R,13S,14R,16R)-19-[2-(dimethylamino)ethylamino]-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamate;hydrochloride
17-DMAG (Alvespimycin) HCl (17-DMAG hydrochloride; KOS-1022; BMS 826476) is a potent inhibitor of Hsp90, binding to Hsp90 with EC50 of 62±29 nM
ChemicalCAS467214-21-7MW653.21FormulaC32H48N4O8·HCl
- CAS number
- 467214-21-7
- Molecular weight
- 653.21
- Formula
- C32H48N4O8·HCl
- Solubility
- ≥ 26·2mg/mL in DMSO
- InChIKey
- DFSYBWLNYPEFJK-QBJGDBLXSA-N
- Catalogue number
- GC13044
- Brand
- GLPBIO
Computed properties PubChem CID 5471033 · TPSA 170 Ų · H-bond donors 5 · H-bond acceptors 10
- TPSA
- 170 Ų
- H-bond donors
- 5
- H-bond acceptors
- 10
- Rotatable bonds
- 8
- Heavy atoms
- 45
SMILES C[C@H]1C[C@H]([C@H]([C@@H](/C=C(/[C@H]([C@@H](/C=C\C=C(\C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCCN(C)C)/C)OC)OC(=O)N)\C)C)O)OC.Cl
Computed descriptors from PubChem (CID 5471033), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il