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Chemical structure of Ripasudil Hydrochloride

GC12817

Ripasudil Hydrochloride

Also listed as K-115 hydrochloride dihydrate

K-115 hydrochloride dihydrate (K-115) is a specific inhibitor of ROCK, with IC50s of 19 and 51 nM for ROCK2 and ROCK1, respectively

ChemicalCAS887375-67-9MW395.88FormulaC15H23ClFN3O4S
CAS number
887375-67-9
Molecular weight
395.88
Formula
C15H23ClFN3O4S
Solubility
≥ 123·2mg/mL in DMSO
InChIKey
CMDJNMACGABCKQ-XVSRHIFFSA-N
Catalogue number
GC12817
Brand
GLPBIO
Computed properties PubChem CID 11625386 · TPSA 72.7 Ų · H-bond donors 4 · H-bond acceptors 8
TPSA
72.7 Ų
H-bond donors
4
H-bond acceptors
8
Rotatable bonds
2
Heavy atoms
25

SMILES C[C@H]1CNCCCN1S(=O)(=O)C2=CC=CC3=CN=CC(=C32)F.O.O.Cl

Computed descriptors from PubChem (CID 11625386), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.