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Chemical structure of C646

GC12733

C646

Also known as 4-[(4E)-4-[[5-(4,5-dimethyl-2-nitrophenyl)furan-2-yl]methylidene]-3-methyl-5-oxopyrazol-1-yl]benzoic acid

C646, a potent and selective p300/CBP histone acetyltransferase inhibitor (Ki 400 nM), has been shown to have pleiotropic activity, including neuroprotective, anti-cancer and anti-epithelial-mesenchymal transition (anti-EMT) effects

ChemicalCAS328968-36-1MW445.42FormulaC24H19N3O6
CAS number
328968-36-1
Molecular weight
445.42
Formula
C24H19N3O6
Solubility
≥ 11·1mg/mL in DMSO
InChIKey
HEKJYZZSCQBJGB-XDHOZWIPSA-N
Catalogue number
GC12733
Brand
GLPBIO
Computed properties PubChem CID 1285940 · XLogP 4.2 · TPSA 129 Ų · H-bond donors 1
XLogP
4.2
TPSA
129 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
4
Heavy atoms
33

SMILES CC1=CC(=C(C=C1C)[N+](=O)[O-])C2=CC=C(O2)/C=C/3\C(=NN(C3=O)C4=CC=C(C=C4)C(=O)O)C

Computed descriptors from PubChem (CID 1285940), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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