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Chemical structure of Cabozantinib S-malate

GC12531

Cabozantinib S-malate

Also listed as Cabozantinib malate (XL184)

Cabozantinib malate (XL184) (XL184 S-malate) is a potent multiple receptor tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl and Flt3 with IC50s of 0·035, 1·3, 4·6, 7 and 11·3 nM, respectively

ChemicalCAS1140909-48-3MW635.59FormulaC32H30FN3O10
CAS number
1140909-48-3
Molecular weight
635.59
Formula
C32H30FN3O10
Solubility
≥ 31·8mg/mL in DMSO
InChIKey
HFCFMRYTXDINDK-WNQIDUERSA-N
Catalogue number
GC12531
Brand
GLPBIO
Computed properties PubChem CID 25102846 · TPSA 194 Ų · H-bond donors 5 · H-bond acceptors 12
TPSA
194 Ų
H-bond donors
5
H-bond acceptors
12
Rotatable bonds
11
Heavy atoms
46

SMILES COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F.C([C@@H](C(=O)O)O)C(=O)O

Computed descriptors from PubChem (CID 25102846), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.