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Chemical structure of NS309

GC12528

NS309

Also known as 6,7-dichloro-3-nitroso-1H-indol-2-ol

NS309 is the most potent positive gating modulator for intermediate-conductance Ca2+-activated K+ channel KCa3·1, with an EC50 of 75nmol/L

ChemicalCAS18711-16-5MW231.04FormulaC8H4Cl2N2O2
CAS number
18711-16-5
Molecular weight
231.04
Formula
C8H4Cl2N2O2
Solubility
DMSO : 100 mg/mL (432·83 mM; Need ultrasonic)
InChIKey
ROBYKNONIPZMTK-UHFFFAOYSA-N
Catalogue number
GC12528
Brand
GLPBIO
Computed properties PubChem CID 135502903 · XLogP 3.2 · TPSA 65.5 Ų · H-bond donors 2
XLogP
3.2
TPSA
65.5 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
0
Heavy atoms
14

SMILES C1=CC(=C(C2=C1C(=C(N2)O)N=O)Cl)Cl

Computed descriptors from PubChem (CID 135502903), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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