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Chemical structure of Pixantrone

GC12503

Pixantrone

Also known as 6,9-bis(2-aminoethylamino)benzo[g]isoquinoline-5,10-dione

Pixantrone (BBR 2778 (free base)), a mitoxantrone analog, is a topoisomerase II inhibitor and DNA intercalator, with anti-tumor activity

ChemicalCAS144510-96-3MW325.37FormulaC17H19N5O2
CAS number
144510-96-3
Molecular weight
325.37
Formula
C17H19N5O2
Solubility
Soluble in DMSO
InChIKey
PEZPMAYDXJQYRV-UHFFFAOYSA-N
Catalogue number
GC12503
Brand
GLPBIO
Computed properties PubChem CID 134019 · XLogP 1 · TPSA 123 Ų · H-bond donors 4
XLogP
1
TPSA
123 Ų
H-bond donors
4
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
24

SMILES C1=CC(=C2C(=C1NCCN)C(=O)C3=C(C2=O)C=NC=C3)NCCN

Computed descriptors from PubChem (CID 134019), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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