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Chemical structure of BMS-911543

GC12454

BMS-911543

Also known as N,N-dicyclopropyl-7-[(1,5-dimethylpyrazol-3-yl)amino]-10-ethyl-3-methyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaene-11-carboxamide

A potent, selective JAK2 inhibitor

ChemicalCAS1271022-90-2MW432.52FormulaC23H28N8O
CAS number
1271022-90-2
Molecular weight
432.52
Formula
C23H28N8O
Solubility
≥ 43·3 mg/mL in DMSO with gentle warming, ≥ 9·8 mg/mL in EtOH with ultrasonic and warming
InChIKey
JCINBYQJBYJGDM-UHFFFAOYSA-N
Catalogue number
GC12454
Brand
GLPBIO
Computed properties PubChem CID 50922691 · XLogP 2.9 · TPSA 85.8 Ų · H-bond donors 1
XLogP
2.9
TPSA
85.8 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
6
Heavy atoms
32

SMILES CCN1C(=CC2=C3C(=C(N=C21)NC4=NN(C(=C4)C)C)N=CN3C)C(=O)N(C5CC5)C6CC6

Computed descriptors from PubChem (CID 50922691), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.