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Chemical structure of EAI045

GC12281

EAI045

Also known as 2-(5-fluoro-2-hydroxyphenyl)-2-(3-oxo-1H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide

Inhibitor of L858R/T790M EGFR mutants

ChemicalCAS1942114-09-1MW383.4FormulaC19H14FN3O3S
CAS number
1942114-09-1
Molecular weight
383.4
Formula
C19H14FN3O3S
Solubility
≥ 38·3mg/mL in DMSO
InChIKey
YTUFHOKUFOQRDF-UHFFFAOYSA-N
Catalogue number
GC12281
Brand
GLPBIO
Computed properties PubChem CID 121231412 · XLogP 2.7 · TPSA 111 Ų · H-bond donors 2
XLogP
2.7
TPSA
111 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
27

SMILES C1C2=CC=CC=C2C(=O)N1C(C3=C(C=CC(=C3)F)O)C(=O)NC4=NC=CS4

Computed descriptors from PubChem (CID 121231412), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.