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Chemical structure of Axitinib

GC12216

Axitinib

Also listed as Axitinib (AG 013736)

Axitinib (AG 013736) is an orally active specific vascular endothelial growth factor receptor (VEGFR) inhibitor that targets VEGFR-1, VEGFR-2, and VEGFR-3 with IC50 values of 0·1nM, 0·2nM, and 0·1-0·3nM, respectively

ChemicalCAS319460-85-0MW386.47FormulaC22H18N4OS
CAS number
319460-85-0
Molecular weight
386.47
Formula
C22H18N4OS
Solubility
≥ 19·3mg/mL in DMSO
InChIKey
RITAVMQDGBJQJZ-FMIVXFBMSA-N
Catalogue number
GC12216
Brand
GLPBIO
Computed properties PubChem CID 6450551 · XLogP 4.2 · TPSA 96 Ų · H-bond donors 2
XLogP
4.2
TPSA
96 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
5
Heavy atoms
28

SMILES CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)/C=C/C4=CC=CC=N4

Computed descriptors from PubChem (CID 6450551), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.