Loading...
Chemical structure of IKK-16 (IKK Inhibitor VII)

GC12180

IKK-16 (IKK Inhibitor VII)

Also known as [4-[[4-(1-benzothiophen-2-yl)pyrimidin-2-yl]amino]phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone

IKK-16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK2, IKK complex and IKK1 with IC50s of 40 nM, 70 nM and 200 nM, respectively

ChemicalCAS873225-46-8MW483.63FormulaC28H29N5OS
CAS number
873225-46-8
Molecular weight
483.63
Formula
C28H29N5OS
Solubility
≥ 23·05mg/mL in DMSO
InChIKey
BWZJBXAPRCVCKQ-UHFFFAOYSA-N
Catalogue number
GC12180
Brand
GLPBIO
Computed properties PubChem CID 9549298 · XLogP 5.3 · TPSA 89.6 Ų · H-bond donors 1
XLogP
5.3
TPSA
89.6 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
35

SMILES C1CCN(C1)C2CCN(CC2)C(=O)C3=CC=C(C=C3)NC4=NC=CC(=N4)C5=CC6=CC=CC=C6S5

Computed descriptors from PubChem (CID 9549298), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.