GC12011
P276-00
Also known as 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(2R,3S)-2-(hydroxymethyl)-1-methylpyrrolidin-3-yl]chromen-4-one;hydrochloride
P276-00 (P276-00) is a potent cyclin-dependent kinase (CDK) inhibitor, which inhibits CDK9-cyclinT1, CDK4-cyclin D1, and CDK1-cyclinB with IC50s of 20 nM, 63 nM, and 79 nM, respectively·P276-00 (P276-00) shows antitumor activity on cisplatin-resistant cells
ChemicalCAS920113-03-7MW438.3FormulaC21H20ClNO5·HCl
- CAS number
- 920113-03-7
- Molecular weight
- 438.3
- Formula
- C21H20ClNO5·HCl
- Solubility
- Soluble in DMSO
- InChIKey
- OOVTUOCTLAERQD-OJMBIDBESA-N
- Catalogue number
- GC12011
- Brand
- GLPBIO
Computed properties PubChem CID 23643975 · TPSA 90.2 Ų · H-bond donors 4 · H-bond acceptors 6
- TPSA
- 90.2 Ų
- H-bond donors
- 4
- H-bond acceptors
- 6
- Rotatable bonds
- 3
- Heavy atoms
- 29
SMILES CN1CC[C@H]([C@@H]1CO)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O.Cl
Computed descriptors from PubChem (CID 23643975), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il