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Chemical structure of AEE788 (NVP-AEE788)

GC11892

AEE788 (NVP-AEE788)

Also known as 6-[4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine

AEE788 (NVP-AEE788) is an inhibitor of the EGFR and ErbB2 with IC50 values of 2 and 6 nM, respectively

ChemicalCAS497839-62-0MW440.58FormulaC27H32N6
CAS number
497839-62-0
Molecular weight
440.58
Formula
C27H32N6
Solubility
≥ 22·05mg/mL in DMSO, ≥ 14·4 mg/mL in EtOH with ultrasonic
InChIKey
OONFNUWBHFSNBT-HXUWFJFHSA-N
Catalogue number
GC11892
Brand
GLPBIO
Computed properties PubChem CID 10297043 · XLogP 4.6 · TPSA 60.1 Ų · H-bond donors 2
XLogP
4.6
TPSA
60.1 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
7
Heavy atoms
33

SMILES CCN1CCN(CC1)CC2=CC=C(C=C2)C3=CC4=C(N3)N=CN=C4N[C@H](C)C5=CC=CC=C5

Computed descriptors from PubChem (CID 10297043), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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