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Chemical structure of Azaguanine-8

GC11843

Azaguanine-8

Also known as 5-amino-2,6-dihydrotriazolo[4,5-d]pyrimidin-7-one

Azaguanine-8 is a purine analogue that shows antineoplastic activity· Azaguanine-8 functions as an antimetabolite and easily incorporates into ribonucleic acids, interfering with normal biosynthetic pathways, thus inhibiting cellular growth

ChemicalCAS134-58-7MW152.11FormulaC4H4N6O
CAS number
134-58-7
Molecular weight
152.11
Formula
C4H4N6O
Solubility
≥ 3·9mg/mL in DMSO, <0·506mg/mL in Water
InChIKey
LPXQRXLUHJKZIE-UHFFFAOYSA-N
Catalogue number
GC11843
Brand
GLPBIO
Computed properties PubChem CID 135403646 · XLogP -1.5 · TPSA 109 Ų · H-bond donors 3
XLogP
-1.5
TPSA
109 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
0
Heavy atoms
11

SMILES C12=NNN=C1N=C(NC2=O)N

Computed descriptors from PubChem (CID 135403646), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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