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Chemical structure of Brivanib

GC11692

Brivanib

Also listed as Brivanib (BMS-540215)

Brivanib (BMS-540215) (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with an IC50 of 25 nM, and has moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β

ChemicalCAS649735-46-6MW370.38FormulaC19H19FN4O3
CAS number
649735-46-6
Molecular weight
370.38
Formula
C19H19FN4O3
Solubility
≥ 18·5mg/mL in DMSO
InChIKey
WCWUXEGQKLTGDX-LLVKDONJSA-N
Catalogue number
GC11692
Brand
GLPBIO
Computed properties PubChem CID 11234052 · XLogP 3 · TPSA 84.7 Ų · H-bond donors 2
XLogP
3
TPSA
84.7 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
27

SMILES CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OC[C@@H](C)O)C

Computed descriptors from PubChem (CID 11234052), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.