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Chemical structure of C-1

GC11605

C-1

Also known as 5-piperazin-1-ylsulfonylisoquinoline

C-1 is a potent protein kinase inhibitor, with IC50s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase, respectively· C-1 also used as a ROCK inhibitor

ChemicalCAS84468-24-6MW277.34FormulaC13H15N3O2S
CAS number
84468-24-6
Molecular weight
277.34
Formula
C13H15N3O2S
Solubility
Soluble in DMSO
InChIKey
UPTYCYWTFGTCCG-UHFFFAOYSA-N
Catalogue number
GC11605
Brand
GLPBIO
Computed properties PubChem CID 3545 · XLogP 0.6 · TPSA 70.7 Ų · H-bond donors 1
XLogP
0.6
TPSA
70.7 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
2
Heavy atoms
19

SMILES C1CN(CCN1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3

Computed descriptors from PubChem (CID 3545), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.