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Chemical structure of Lexibulin

GC11383

Lexibulin

Also listed as CYT997 (Lexibulin)

CYT997 (Lexibulin) (CYT-997) is a potent and orally active tubulin polymerisation inhibitor with IC50s of 10-100 nM in cancer cell lines; with potent cytotoxic and vascular disrupting activity in vitro and in vivo· CYT997 (Lexibulin) induces cell apoptosis and induces mitochondrial ROS generation in GC cells

ChemicalCAS917111-44-5MW434.53FormulaC24H30N6O2
CAS number
917111-44-5
Molecular weight
434.53
Formula
C24H30N6O2
Solubility
DMF： 20 mg/ml,DMF：PBS (pH 7·2) (1：20)： 0·04 mg/ml,DMSO： 20 mg/ml,Ethanol： 16 mg/ml
InChIKey
MTJHLONVHHPNSI-IBGZPJMESA-N
Catalogue number
GC11383
Brand
GLPBIO
Computed properties PubChem CID 11351021 · XLogP 3.6 · TPSA 101 Ų · H-bond donors 3
XLogP
3.6
TPSA
101 Ų
H-bond donors
3
H-bond acceptors
6
Rotatable bonds
9
Heavy atoms
32

SMILES CCC[C@@H](C1=CN=CC=C1)NC2=NC(=NC=C2C)C3=CC(=C(C=C3)NC(=O)NCC)OC

Computed descriptors from PubChem (CID 11351021), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.