
GC11336
Motesanib Diphosphate
Also listed as Motesanib Diphosphate (AMG-706)
Motesanib Diphosphate (AMG-706) (AMG 706 Diphosphate) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50s of 2 nM/3 nM/6 nM, respectively, and has similar activity against Kit, and is approximately 10-fold more selective for VEGFR than PDGFR and Ret
ChemicalCAS857876-30-3MW569.44FormulaC22H23N5O·2H3PO4
- CAS number
- 857876-30-3
- Molecular weight
- 569.44
- Formula
- C22H23N5O·2H3PO4
- Solubility
- ≥ 28·45mg/mL in DMSO, ≥ 3·47 mg/mL in EtOH with ultrasonic
- InChIKey
- ONDPWWDPQDCQNJ-UHFFFAOYSA-N
- Catalogue number
- GC11336
- Brand
- GLPBIO
Computed properties PubChem CID 16097729 · TPSA 234 Ų · H-bond donors 9 · H-bond acceptors 13
- TPSA
- 234 Ų
- H-bond donors
- 9
- H-bond acceptors
- 13
- Rotatable bonds
- 5
- Heavy atoms
- 38
SMILES CC1(CNC2=C1C=CC(=C2)NC(=O)C3=C(N=CC=C3)NCC4=CC=NC=C4)C.OP(=O)(O)O.OP(=O)(O)O
Computed descriptors from PubChem (CID 16097729), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il