GC11251
NU7441 (KU-57788)
Also known as 8-dibenzothiophen-4-yl-2-morpholin-4-ylchromen-4-one
NU7441 (KU-57788) is a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor with an IC50 of 13nM· NU7441 also inhibits phosphatidylinositol 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) with IC50 of 5·0 and 1·7μM, respectively
ChemicalCAS503468-95-9MW413.49FormulaC25H19NO3S
- CAS number
- 503468-95-9
- Molecular weight
- 413.49
- Formula
- C25H19NO3S
- Solubility
- ≥ 4·13mg/mL in DMSO, ＜2·48 mg/mL in EtOH, ＜2·56 mg/mL in Water
- InChIKey
- JAMULYFATHSZJM-UHFFFAOYSA-N
- Catalogue number
- GC11251
- Brand
- GLPBIO
Computed properties PubChem CID 11327430 · XLogP 5.5 · TPSA 67 Ų · H-bond donors 0
- XLogP
- 5.5
- TPSA
- 67 Ų
- H-bond donors
- 0
- H-bond acceptors
- 5
- Rotatable bonds
- 2
- Heavy atoms
- 30
SMILES C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC5=C4SC6=CC=CC=C56
Computed descriptors from PubChem (CID 11327430), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il