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Chemical structure of RN486

GC11230

RN486

Also known as 6-cyclopropyl-8-fluoro-2-[2-(hydroxymethyl)-3-[1-methyl-5-[[5-(4-methylpiperazin-1-yl)-2-pyridinyl]amino]-6-oxo-3-pyridinyl]phenyl]isoquinolin-1-one

Btk inhibitor,potent and selective

ChemicalCAS1242156-23-5MW606.69FormulaC35H35FN6O3
CAS number
1242156-23-5
Molecular weight
606.69
Formula
C35H35FN6O3
Solubility
≥ 30·35mg/mL in DMSO with gentle warming
InChIKey
ZTUJNJAKTLHBEX-UHFFFAOYSA-N
Catalogue number
GC11230
Brand
GLPBIO
Computed properties PubChem CID 46908026 · XLogP 3.8 · TPSA 92.3 Ų · H-bond donors 2
XLogP
3.8
TPSA
92.3 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
7
Heavy atoms
45

SMILES CN1CCN(CC1)C2=CN=C(C=C2)NC3=CC(=CN(C3=O)C)C4=C(C(=CC=C4)N5C=CC6=CC(=CC(=C6C5=O)F)C7CC7)CO

Computed descriptors from PubChem (CID 46908026), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.