GC11008
Necrostatin-1
Also known as 5-(1H-indol-3-ylmethyl)-3-methyl-2-sulfanylideneimidazolidin-4-one
Necrostatin-1 mainly acts on RIP1 in cells [5], Necrostatin-1 is a RIP1 kinase inhibitor with an IC50 value of 0·32 mM
ChemicalCAS4311-88-0MW259.33FormulaC13H13N3OS
- CAS number
- 4311-88-0
- Molecular weight
- 259.33
- Formula
- C13H13N3OS
- Solubility
- ≥ 12·97 mg/mL in DMSO, ≥ 13·29 mg/mL in EtOH with ultrasonic
- InChIKey
- TXUWMXQFNYDOEZ-UHFFFAOYSA-N
- Catalogue number
- GC11008
- Brand
- GLPBIO
Computed properties PubChem CID 2828334 · XLogP 1.9 · TPSA 80.2 Ų · H-bond donors 2
- XLogP
- 1.9
- TPSA
- 80.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 2
- Rotatable bonds
- 2
- Heavy atoms
- 18
SMILES CN1C(=O)C(NC1=S)CC2=CNC3=CC=CC=C32
Computed descriptors from PubChem (CID 2828334), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il