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Chemical structure of WP1130

GC10970

WP1130

Also known as (E)-3-(6-bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylbutyl]prop-2-enamide

WP1130 (WP1130) is a cell-permeable deubiquitinase (DUB) inhibitor, directly inhibiting DUB activity of USP9x, USP5, USP14, and UCH37· WP1130 has been shown to downregulate the antiapoptotic proteins Bcr-Abl and JAK2

ChemicalCAS856243-80-6MW384.27FormulaC19H18BrN3O
CAS number
856243-80-6
Molecular weight
384.27
Formula
C19H18BrN3O
Solubility
≥ 38·4mg/mL in DMSO
InChIKey
LIDOPKHSVQTSJY-VMEIHUARSA-N
Catalogue number
GC10970
Brand
GLPBIO
Computed properties PubChem CID 11222830 · XLogP 4.3 · TPSA 65.8 Ų · H-bond donors 1
XLogP
4.3
TPSA
65.8 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
6
Heavy atoms
24

SMILES CCC[C@@H](C1=CC=CC=C1)NC(=O)/C(=C/C2=NC(=CC=C2)Br)/C#N

Computed descriptors from PubChem (CID 11222830), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.