Loading...
Chemical structure of [D-Trp8]-γ-MSH

GC10947

[D-Trp8]-γ-MSH

Also known as (3S)-3-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-4-methylsulfanylbutanoyl]amino]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-[[(2S)-5-carbamimidamido-1-[[(2S)-1-(carboxymethylamino)-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopentan-2-yl]amino]-4-oxobutanoic acid

[D-Trp8]-γ-MSH is a potent and selective agonist of melanocortin 3 (MC3) receptor, with IC50s of 6·7 nM, 600 nM and 340 nM for hMC3, hMC4 and hMC5, respectively in CHO cells

ChemicalCAS321351-81-9MW1570.79FormulaC74H99N21O16S
CAS number
321351-81-9
Molecular weight
1570.79
Formula
C74H99N21O16S
Solubility
Soluble to 1 mg/ml in Water
InChIKey
GZWUQPQBOGLSIM-MDMVXOTPSA-N
Catalogue number
GC10947
Brand
GLPBIO
Computed properties PubChem CID 16158468 · XLogP -1.6 · TPSA 635 Ų · H-bond donors 23
XLogP
-1.6
TPSA
635 Ų
H-bond donors
23
H-bond acceptors
21
Rotatable bonds
49
Heavy atoms
112

SMILES CC(C)[C@@H](C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](CC3=CNC4=CC=CC=C43)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC5=CC=CC=C5)C(=O)NCC(=O)O)NC(=O)[C@H](CC6=CC=C(C=C6)O)N

Computed descriptors from PubChem (CID 16158468), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.