GC10946
5-Azacytidine
Also known as 4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
5-Azacytidine (also known as 5-AzaC), a compound belonging to a class of cytosine analogues, is a DNA methyl transferase (DNMT) inhibitor that exerts potent cytotoxicity against multiple myeloma (MM) cells, including MM·1S, MM·1R, RPMI-8266, RPMI-LR5, RPMI-Dox40 and Patient-derived MM, with the half maximal inhibition concentration IC50 values of 1·5 μmol/L, 0·7 μmol/L, 1·1 μmol/L, 2·5 μmol/L, 3·2 μmol/L and 1·5 μmol/L respectively
ChemicalCAS320-67-2MW244.2FormulaC8H12N4O5
- CAS number
- 320-67-2
- Molecular weight
- 244.2
- Formula
- C8H12N4O5
- Solubility
- ≥ 12·21mg/mL in DMSO
- InChIKey
- NMUSYJAQQFHJEW-UHFFFAOYSA-N
- Catalogue number
- GC10946
- Brand
- GLPBIO
Computed properties PubChem CID 1805 · XLogP -2.2 · TPSA 141 Ų · H-bond donors 4
- XLogP
- -2.2
- TPSA
- 141 Ų
- H-bond donors
- 4
- H-bond acceptors
- 5
- Rotatable bonds
- 2
- Heavy atoms
- 17
SMILES C1=NC(=NC(=O)N1C2C(C(C(O2)CO)O)O)N
Computed descriptors from PubChem (CID 1805), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il