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Chemical structure of SCH 23390 hydrochloride

GC10892

SCH 23390 hydrochloride

Also known as (5R)-8-chloro-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol;hydrochloride

SCH 23390 hydrochloride is a highly potent and selective dopamine D1-like receptor antagonist with a K(i) of 0·2 and 0·3 nM for the D1 and D5 dopamine receptor subtypes, respectively

ChemicalCAS125941-87-9MW324.24FormulaC17H18ClNO·HCl
CAS number
125941-87-9
Molecular weight
324.24
Formula
C17H18ClNO·HCl
Solubility
DMF: 15 mg/ml,DMSO: 20 mg/ml,DMSO:PBS (pH 7·2) (1:7): 0·12 mg/ml,Ethanol: 5 mg/ml
InChIKey
OYCAEWMSOPMASE-XFULWGLBSA-N
Catalogue number
GC10892
Brand
GLPBIO
Computed properties PubChem CID 11957535 · TPSA 23.5 Ų · H-bond donors 2 · H-bond acceptors 2
TPSA
23.5 Ų
H-bond donors
2
H-bond acceptors
2
Rotatable bonds
1
Heavy atoms
21

SMILES CN1CCC2=CC(=C(C=C2[C@H](C1)C3=CC=CC=C3)O)Cl.Cl

Computed descriptors from PubChem (CID 11957535), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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