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Chemical structure of clozapine N-oxide

GC10822

clozapine N-oxide

Also listed as Clozapine N-oxide (CNO)

Clozapine N-oxide(CNO) is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor (EC50=11 nM) agonist

ChemicalCAS34233-69-7MW342.82FormulaC18H19ClN4O
CAS number
34233-69-7
Molecular weight
342.82
Formula
C18H19ClN4O
Solubility
≥ 17·15 mg/mL in DMSO, ≥ 49 mg/mL in Water with gentle warmingThis product is unstable in solution and it is recommended to prepare and use it immediately·
InChIKey
OGUCZBIQSYYWEF-UHFFFAOYSA-N
Catalogue number
GC10822
Brand
GLPBIO
Computed properties PubChem CID 135445691 · XLogP 2.5 · TPSA 45.7 Ų · H-bond donors 1
XLogP
2.5
TPSA
45.7 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
1
Heavy atoms
24

SMILES C[N+]1(CCN(CC1)C2=NC3=C(C=CC(=C3)Cl)NC4=CC=CC=C42)[O-]

Computed descriptors from PubChem (CID 135445691), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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