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Chemical structure of ATC 0175 hydrochloride

GC10700

ATC 0175 hydrochloride

Also known as N-[4-[[4-(dimethylamino)quinazolin-2-yl]amino]cyclohexyl]-3,4-difluorobenzamide;hydrochloride

ATC 0175 hydrochloride is a potent, selective and orally active melanin-concentrating hormone 1 recepter antagonist with IC50s of 13·5, >10000 nM for MCH1R, MCH2R, respectively

ChemicalCAS510733-97-8MW461.94FormulaC23H25F2N5O·HCl
CAS number
510733-97-8
Molecular weight
461.94
Formula
C23H25F2N5O·HCl
Solubility
<11·55mg/ml in ethanol
InChIKey
HUUPKFUYSQNNLO-UHFFFAOYSA-N
Catalogue number
GC10700
Brand
GLPBIO
Computed properties PubChem CID 9934032 · TPSA 70.2 Ų · H-bond donors 3 · H-bond acceptors 7
TPSA
70.2 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
32

SMILES CN(C)C1=NC(=NC2=CC=CC=C21)NC3CCC(CC3)NC(=O)C4=CC(=C(C=C4)F)F.Cl

Computed descriptors from PubChem (CID 9934032), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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