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Chemical structure of Fruquintinib

GC10355

Fruquintinib

Also listed as Fruquintinib(HMPL-013)

Fruquintinib(HMPL-013) (HMPL-013) is a highly potent and selective VEGFR 1/2/3 inhibitor with IC50s of 33, 0·35, and 35 nM, respectively

ChemicalCAS1194506-26-7MW393.39FormulaC21H19N3O5
CAS number
1194506-26-7
Molecular weight
393.39
Formula
C21H19N3O5
Solubility
≥ 6·35mg/mL in DMSO
InChIKey
BALLNEJQLSTPIO-UHFFFAOYSA-N
Catalogue number
GC10355
Brand
GLPBIO
Computed properties PubChem CID 44480399 · XLogP 3.4 · TPSA 95.7 Ų · H-bond donors 1
XLogP
3.4
TPSA
95.7 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
29

SMILES CC1=C(C2=C(O1)C=C(C=C2)OC3=NC=NC4=CC(=C(C=C43)OC)OC)C(=O)NC

Computed descriptors from PubChem (CID 44480399), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.