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Chemical structure of alpha-APP Modulator

GC10343

alpha-APP Modulator

Also listed as α-Amyloid Precursor Protein Modulator

α-Amyloid Precursor Protein Modulator is a cell-permeable benzolactam-derived protein kinase C (PKC) activator with a Ki of 11·9 nM

ChemicalCAS497259-23-1MW501.54FormulaC27H30F3N3O3
CAS number
497259-23-1
Molecular weight
501.54
Formula
C27H30F3N3O3
Solubility
25·08mg/mL in DMSO
InChIKey
WOLVEMPZUIFSII-IHHOKICGSA-N
Catalogue number
GC10343
Brand
GLPBIO
Computed properties PubChem CID 9935767 · XLogP 5 · TPSA 81.7 Ų · H-bond donors 3
XLogP
5
TPSA
81.7 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
36

SMILES CC(C)[C@H]1C(=O)N[C@@H](CC2=C(N1C)C=CC(=C2)NC(=O)/C=C/C=C/C3=CC=C(C=C3)C(F)(F)F)CO

Computed descriptors from PubChem (CID 9935767), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.