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Chemical structure of Bazedoxifene HCl

GC10245

Bazedoxifene HCl

Also known as 1-[[4-[2-(azepan-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methylindol-5-ol;hydrochloride

Bazedoxifene HCl (TSE-424 hydrochloride) is an oral active, BBB-penetrant nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively· Bazedoxifene HCl can be used for the research of osteoporosis· Bazedoxifene HCl acts as an inhibitor of IL-6/GP130 protein-protein interactions· Bazedoxifene HCl can be used for the research of pancreatic cancer

ChemicalCAS198480-56-7MW507.06FormulaC30H34N2O3·HCl
CAS number
198480-56-7
Molecular weight
507.06
Formula
C30H34N2O3·HCl
Solubility
≥ 25·35mg/mL in DMSO
InChIKey
COOWZQXURKSOKE-UHFFFAOYSA-N
Catalogue number
GC10245
Brand
GLPBIO
Computed properties PubChem CID 9936012 · TPSA 57.9 Ų · H-bond donors 3 · H-bond acceptors 4
TPSA
57.9 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
7
Heavy atoms
36

SMILES CC1=C(N(C2=C1C=C(C=C2)O)CC3=CC=C(C=C3)OCCN4CCCCCC4)C5=CC=C(C=C5)O.Cl

Computed descriptors from PubChem (CID 9936012), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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