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Chemical structure of Ivabradine HCl

GC10194

Ivabradine HCl

Also known as 3-[3-[[(7S)-3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one;hydrochloride

Ivabradine HCl is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If)

ChemicalCAS148849-67-6MW505.05FormulaC27H37ClN2O5
CAS number
148849-67-6
Molecular weight
505.05
Formula
C27H37ClN2O5
Solubility
≥ 25·25mg/mL in DMSO
InChIKey
HLUKNZUABFFNQS-ZMBIFBSDSA-N
Catalogue number
GC10194
Brand
GLPBIO
Computed properties PubChem CID 3045381 · TPSA 60.5 Ų · H-bond donors 1 · H-bond acceptors 6
TPSA
60.5 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
10
Heavy atoms
35

SMILES CN(CCCN1CCC2=CC(=C(C=C2CC1=O)OC)OC)C[C@H]3CC4=CC(=C(C=C34)OC)OC.Cl

Computed descriptors from PubChem (CID 3045381), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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