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Chemical structure of H 89 2HCl

GC10074

H 89 2HCl

Also known as N-[2-[[(E)-3-(4-bromophenyl)prop-2-enyl]amino]ethyl]isoquinoline-5-sulfonamide;dihydrochloride

H-89 2HCl is A potent and selective camp-dependent protein kinase A inhibitor with IC50 value of 48 nM, showing weak inhibition of PKG,PKC,Casein kinase and other kinases

ChemicalCAS130964-39-5MW519.28FormulaC20H20BrN3O22HCl
CAS number
130964-39-5
Molecular weight
519.28
Formula
C20H20BrN3O22HCl
Solubility
≥ 51·9mg/mL in DMSO
InChIKey
GELOGQJVGPIKAM-WTVBWJGASA-N
Catalogue number
GC10074
Brand
GLPBIO
Computed properties PubChem CID 5702541 · TPSA 79.5 Ų · H-bond donors 4 · H-bond acceptors 5
TPSA
79.5 Ų
H-bond donors
4
H-bond acceptors
5
Rotatable bonds
8
Heavy atoms
29

SMILES C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCNC/C=C/C3=CC=C(C=C3)Br.Cl.Cl

Computed descriptors from PubChem (CID 5702541), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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